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news & events / press releases / 2003 index / Press Release June 2003 CHIP CHEMICAL INKJET PRINTER A new solution for micro-scale proteomics from Shimadzu Biotech and Proteome Systems June 8th, 2003. The new Chemical Inkjet Printer (CHIP) from Shimadzu Biotech and Proteome Systems offers researchers a revolutionary new approach to Peptide Mass Fingerprinting (PMF) and Protein Macroarray Analysis. Developed in conjunction with the leading proteomics company Proteome Systems, CHIP is a unique technology platform for micro-scale on-membrane protein identification and characterization with widespread applications in biomedical and diagnostic discovery. Many important proteins are only available in limited amounts for multiple proteomics investigations and unlike DNA, there is no process equivalent to PCR to amplify proteins. Using current methods, the entire sample on a protein array is sacrificed in order to perform identification and characterization. CHIP employs state-of-the-art nanotechnology fluidics, enabling microprinting to be carried out on just a fraction of a protein spot. This allows further study on the remainder of bioactive materials, which could prove invaluable for precious clinical samples. CHIP’s piezoelectric ‘drop-on-demand’ ink-jet technology allows for the precise delivery of picolitre volumes of reagents to defined locations on a PVDF membrane. The system can deliver up to four different chemistries to the same spot, allowing for multiple enzyme digests on one spot and thereby increasing sequence coverage of a protein. Using CHIP, proteomics researchers can save time and resources as they no longer have to carry out time-consuming in-gel digestion, peptide extraction and C18 ZipTip® clean-up steps. The technology can also rapidly dispense multiple antibodies to screen for antigens in minutes rather than hours, transforming previously slow and labour-intensive Western blotting protocols into rapid, quantitative and automated techniques. Dr Tetsuo Ichikawa, Chairman of Shimadzu Biotech commented, “ The Chemical Inkjet Printer represents a completely new approach to micro-scale proteomics research, especially as it can seamlessly integrate with our AXIMA family of MALDI TOF instruments for protein identification.” Keith Williams, CEO of Proteome Systems, said, " The Chemical
Inkjet Printer is the pivotal technology to evolve from the relationship
with Shimadzu Biotech. With its ability to integrate with both Shimadzu
Biotech’s AXIMA instruments and our ProteomIQTM platform for
high-throughput proteomics, we believe that the Chemical Inkjet
Printer will become a defining instrument in any large scale proteomics
program.” -ends-
Shimadzu Biotech is a business unit of Shimadzu Corporation. It has been created to unite a strong solutions-based offering and accelerate the progress of biotechnology research and development. Shimadzu Biotech captures, within one dedicated organisation, the best expertise and technology from within Shimadzu Corporation and its subsidiary, Kratos Analytical. About Proteome Systems Proteome Systems is a leading proteomics technology, diagnostics and discovery company. Proteome Systems has R&D and manufacturing facilities in Sydney, Australia and Boston, USA. Proteome Systems also has a contract services joint* venture in Worcester, USA (Charles River Proteomics Services Inc – a joint venture with Charles River Laboratories), and a joint venture (Proteome Systems Japan) with Itochu Corporation in Tokyo, Japan. For more information, please contact:Shimadzu Biotech Chris Sutton, Business Manager Proteome Systems Limited For press information, please contact: Richard Anderson
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