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Press Release July 2004

SHIMADZU BIOTECH AND PROTEOME SYSTEMS WIN R&D 100 AWARD FOR NOVEL CHEMICAL INKJET PRINTER (CHIP) TECHNOLOGY

Kyoto, Japan and Sydney, Australia- July 21 2004. Shimadzu Biotech, a global business unit of Shimadzu Corporation and Proteome Systems today announced that their jointly developed Chemical InkJet Printer (CHIP 1000) has been selected as one of the 100 most technologically significant products introduced into the marketplace over the past year. The R&D 100 award was bestowed by the independent judging panel and editors of R&D Magazine, in what was highlighted as a very competitive year of nominations.

The novel CHIP technology offers researchers a revolutionary new approach to automatic protein processing, identification and characterisation. Developed jointly by Shimadzu Biotech and Proteome Systems with financial support from the Australian Government's START Program, the CHIP is a unique technology platform for executing micro-scale on-membrane chemistry that will have widespread applications in biomedical research and biomarker discovery.

"This award is an exciting accomplishment for our joint development program with Proteome Systems" said Dr Tetsuo Ichikawa, Chairman of Shimadzu Biotech. "Shimadzu Biotech has enjoyed the opportunity of working with Proteome Systems and the quality of the outcome of our efforts is evidenced in being selected for the R&D 100 Award. Shimadzu is very proud."


The newly released CHIP-1000 employs state-of-the-art piezoelectric 'drop-on-demand' ink-jet technology developed by MicroFab Technologies in USA, enabling microdispensing of biochemicals and reagents on just a fraction of the protein purified by electrophoresis. This allows further study on the remainder of the protein, which could prove invaluable for precious samples such as clinical biopsies and related samples. The CHIP-1000 represents the first product to use the technology described in Proteome Systems' recently granted US patent (No. 6,701,254) entitled "Method for analyzing samples of biomolecules in an array".

Dr Andrew Gooley, Chief Scientific Officer of Proteome Systems and inventor of the CHIP technology commented, "the award is indeed a very proud moment for Proteome Systems. Our team developed the CHIP prototype in Sydney and then worked with Shimadzu towards the commercial release of the CHIP-1000. Partnering with a quality scientific instrument manufacturer such as Shimadzu has been a very rewarding experience for our company".

The prestigious R&D 100 Awards have been presented annually for 42 years. The winning of an R&D 100 Award provides a mark of excellence known to industry, government, and academia as proof that the product is one of the most innovative ideas of the year. The full list of winners will be announced in the September 2004 issue of R&D Magazine.

-ends-


About Shimadzu Biotech

Shimadzu Biotech is a business unit of Shimadzu Corporation. It has been created to unite a strong solutions-based offering and accelerate the progress of biotechnology research and development. Shimadzu Biotech captures, within one dedicated organisation, the best expertise and technology from within Shimadzu Corporation and its subsidiary, Kratos Analytical.

About Proteome Systems

Proteome Systems develops and commercialises innovative technology solutions for proteomics based research. These solutions include integrated instrument-based systems, consumables and bioinformatic software. The company applies its technology platforms and expertise to discover and validate diagnostic and drug targets and to commercialise novel diagnostic products.

For more information, please contact:

Shimadzu Biotech
Dr Tetsuo Ichikawa, Chairman
Tel: +81-75-823-1148
Fax: +81-75-823-1364
email: tichi@shimadzu.co.jp
Website: www.shimadzu-biotech.net

Proteome Systems Limited
Dr Andrew Gooley, Head of Technology & Chief Scientific Officer
Tel: 61-2-9889-1830
Fax: 61-2-9889-1805
email: andrew.gooley@proteomesystems.com
Website: http://www.proteomesystems.com

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