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news & events / press releases / 2005 index /
Press Release February 2005
LCMS-IT-TOF LIQUID CHROMATOGRAPH / MASS SPECTROMETER FEATURES MSN CAPABILITY
Shimadzu Scientific Instruments has introduced the LCMS-IT-TOF Liquid Chromatograph/Mass
Spectrometer, a novel hybrid mass spectrometer for biomarker discovery, metabolite
identification and proteomics research. Coupling atmospheric pressure ionization with Ion-Trap
(IT) and Time-of-Flight (TOF) technologies, the LCMS-IT-TOF delivers high mass accuracy and
high mass resolution (10,000 at 1000 m/z) independent of MS mode.
Shimadzu's LCMS-IT-TOF has been designed to maximize sensitivity and selectivity by
optimizing the ion transport to the TOF analyzer and redefining the capability of the quadrupole
ion trap. The ion trap is not only used to focus ions before ejection into the TOF, but it also
supports fragmentation, MSn analysis and a high precursor ion selection (resolution > 1,000 at
1,000 m/z). A high precursor ion selection allows specific ions to be isolated for further
fragmentation, simplifying MS/MS data interpretation and enhancing the selectivity of detection,
particularly from complex matrices. A fast polarity switching speed (100ms to switch between
positive and negative ionization), combined with Compressed Ion Injection (patented), Ballistic
Ion Extraction (patent pending), and Dual-Stage Reflectron (patent pending) technology, creates a
true benchmark for biomarker discovery, metabolite identification, and proteomics research.
-ends-
For more information, call 800-477-1227, Fax: 410-381-1222, visit our web site at
www.ssi.shimadzu.com or write Shimadzu Scientific Instruments, Inc., 7102 Riverwood Drive,
Columbia, MD 21046.
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